|
|
Cartilage, typically comprised of 60-80% water with a mass balance primarily of collagen, is the prototypical biologic hydrogel.
The physical properties of Carticept Medical’s proprietary hydrogel, Cartiva™ SCI, make it an excellent replacement for
damaged articular cartilage.
The water content of the Cartiva cryogel is similar to surrounding healthy cartilage and is osmotically balanced with
the fluids and tissues within the joint. Stringent control of the PVA composition and the freeze/thaw process results
in compressive properties (aggregate modulus and creep) and wear resistance similar to native cartilage.2 In addition,
this cryogel exhibits a low coefficient of friction due to fluid-film formation upon loading.3
1 Data on file, Carticept Medical, Inc.
2 Swieszkowski W, et al. An elastic material for cartilage replacement in an arthritic shoulder joint.
Biomaterials. 2006; 27(8):1534-41.
3 Murakami T, et al. Adaptive multimode lubrication in natural synovial joints and artificial joints, Proc Inst Mech Eng H. 1998;212(1):23-35. |
 |
|
|
| Property |
Articular Cartilage |
Cartiva™ SCI1 |
| Water Content |
60-80% |
60% |
| Compressive Modulus |
0.5 to 1.0 MPa |
2.5 - 3.0 MPa |
| Coefficient of Friction |
<0.01 - 0.05 |
0.04 - 0.07 |
*Moduli of other cartilage replacements are typically >100GPa
|
